Molecular basis of endothelial dysfunction in sepsis.

@article{Peters2003MolecularBO,
  title={Molecular basis of endothelial dysfunction in sepsis.},
  author={K. Peters and R. Unger and J. Brunner and C. Kirkpatrick},
  journal={Cardiovascular research},
  year={2003},
  volume={60 1},
  pages={
          49-57
        }
}
Sepsis is one of the major causes of mortality in critically ill patients and develops as a result of the host response to infection. A complex network of events is set into motion in the body by the infection and results in the pathogenesis of sepsis. This review article focuses on the molecular mechanisms and components involved in the pathogenesis of sepsis with a major emphasis on the endothelium. This includes sepsis-inducing bacterial components (e.g. endotoxins), cellular targets of… Expand

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