Molecular basis of cellular response to cisplatin chemotherapy in non-small cell lung cancer (Review).

@article{Wang2004MolecularBO,
  title={Molecular basis of cellular response to cisplatin chemotherapy in non-small cell lung cancer (Review).},
  author={Gangduo Wang and Eddie B. Reed and Qingdi Quentin Li},
  journal={Oncology reports},
  year={2004},
  volume={12 5},
  pages={955-65}
}
Cisplatin is one of the most potent anticancer agents, displaying significant clinical activity against a variety of solid tumors. For more than two decades, the most effective systemic chemotherapy for non-small cell lung cancer (NSCLC), the leading cause of cancer morbidity and mortality among men and women in the western world, was cisplatin-based combination treatment. Unfortunately, the outcome of cisplatin therapy on NSCLC seems to have reached a plateau. Therefore, the biological… CONTINUE READING
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