Molecular basis of beta-thalassemia in Thai Muslim patients in the the south of Thailand.

@article{Laosombat1997MolecularBO,
  title={Molecular basis of beta-thalassemia in Thai Muslim patients in the the south of Thailand.},
  author={Vichai Laosombat and C Nopparatana and Malai Wongchanchailert and Aranya Wiriyasateinkul},
  journal={The Southeast Asian journal of tropical medicine and public health},
  year={1997},
  volume={28 Suppl 3},
  pages={104-5}
}
Among a sample of 29 unrelated Thai Muslim children, a total of 37 beta thalassemia genes was identified and 33 out of 37 mutations (89%) were characterized giving 6 different mutations. Four mutations [IVS-1 nt 5 (G-C), codon 19 (A-G), codons 41/42 (-CTTT) and IVS-1 nt 1 (G-T)] account for 86%. IVS-1 nt 5 (G-C) is the most common mutation found in Thai Muslim patients. Thai Muslim patients share the four most common mutations with Malays. 

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