Molecular basis of ancestral vertebrate electroreception

  title={Molecular basis of ancestral vertebrate electroreception},
  author={Nicholas W. Bellono and Duncan B. Leitch and David Julius},
Elasmobranch fishes, including sharks, rays, and skates, use specialized electrosensory organs called ampullae of Lorenzini to detect extremely small changes in environmental electric fields. Electrosensory cells within these ampullae can discriminate and respond to minute changes in environmental voltage gradients through an unknown mechanism. Here we show that the voltage-gated calcium channel CaV1.3 and the big conductance calcium-activated potassium (BK) channel are preferentially expressed… CONTINUE READING