Molecular basis of R-type calcium channels in central amygdala neurons of the mouse.

@article{Lee2002MolecularBO,
  title={Molecular basis of R-type calcium channels in central amygdala neurons of the mouse.},
  author={Seung-Chan Lee and Sukwoo Choi and Taehoon Lee and Hyung-Lae Kim and Hemin Chin and Hee-sup Shin},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2002},
  volume={99 5},
  pages={3276-81}
}
R-type Ca2+ channels play a critical role in coupling excitability to dendritic Ca2+ influx and neuronal secretion. Unlike other types of voltage-sensitive Ca2+ channels (L, N, P/Q, and T type), the molecular basis for the R-type Ca2+ channel is still unclear, thereby limiting further detailed analyses of R-type Ca2+ channel physiology. The prevailing hypothesis is that alpha(1E) (Ca(V)2.3) gene encodes for R-type Ca2+ channels, but the dearth of critical evidence has rendered this hypothesis… CONTINUE READING

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