Molecular basis governing primary sex in mammals

  • Kozo Nagai
  • Published 1996 in Japanese Journal of Human Genetics

Abstract

SummaryThe function of Sry for inducing a male gonad was identified due to a development of a transgenic XX male mouse with testes by introducing a single gene into an embryo. The intronless Sry encodes a putative transcriptional protein harboring an HMG motif. The sequence similarity within the HMG motif has been highly conserved despite less conservation… (More)
DOI: 10.1007/BF01876327

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