Molecular basis for specificity of nuclear import and prediction of nuclear localization.

@article{Marfori2011MolecularBF,
  title={Molecular basis for specificity of nuclear import and prediction of nuclear localization.},
  author={Mary Marfori and Andrew V Mynott and Jonathan J Ellis and Ahmed M. Mehdi and Neil F. W. Saunders and Paul M. G. Curmi and Jade K Forwood and Mikael Bod{\'e}n and Bostjan Kobe},
  journal={Biochimica et biophysica acta},
  year={2011},
  volume={1813 9},
  pages={1562-77}
}
Although proteins are translated on cytoplasmic ribosomes, many of these proteins play essential roles in the nucleus, mediating key cellular processes including but not limited to DNA replication and repair as well as transcription and RNA processing. Thus, understanding how these critical nuclear proteins are accurately targeted to the nucleus is of paramount importance in biology. Interaction and structural studies in the recent years have jointly revealed some general rules on the… CONTINUE READING
Highly Influential
This paper has highly influenced 21 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS

Citations

Publications citing this paper.
Showing 1-10 of 125 extracted citations

Regulation of nucleocytoplasmic transport in skeletal muscle.

Current topics in developmental biology • 2011
View 6 Excerpts
Highly Influenced

References

Publications referenced by this paper.
Showing 1-10 of 157 references

Systematic identification of cell cycle-dependent yeast nucleocytoplasmic shuttling proteins by prediction of composite motifs.

Proceedings of the National Academy of Sciences of the United States of America • 2009
View 19 Excerpts
Highly Influenced

Finding nuclear localization signals.

View 7 Excerpts
Highly Influenced

The Universal Protein Resource (UniProt) in 2010

Nucleic Acids Research • 2010
View 6 Excerpts
Highly Influenced

Adams-Collier, K.Nakai,WoLF PSORT: protein localization predictor

P.Horton, K. J. Park, T.Obayashi, N. Fujita, C.J.H.Harada
Nucleic Acids Res • 2007
View 6 Excerpts
Highly Influenced

LOCATE: a mouse protein subcellular localization database

Nucleic Acids Research • 2006
View 6 Excerpts
Highly Influenced

Dissection of a nuclear localization signal.

The Journal of biological chemistry • 2001
View 7 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…