Molecular basis for coupling the plasma membrane to the actin cytoskeleton during clathrin-mediated endocytosis.

@article{Skrun2012MolecularBF,
  title={Molecular basis for coupling the plasma membrane to the actin cytoskeleton during clathrin-mediated endocytosis.},
  author={Michal Skru{\vz}n{\'y} and Thorsten Brach and Rodolfo Ciuffa and Sofia Rybina and Malte Wachsmuth and Marko Kaksonen},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2012},
  volume={109 38},
  pages={E2533-42}
}
Dynamic actin filaments are a crucial component of clathrin-mediated endocytosis when endocytic proteins cannot supply enough energy for vesicle budding. Actin cytoskeleton is thought to provide force for membrane invagination or vesicle scission, but how this force is transmitted to the plasma membrane is not understood. Here we describe the molecular mechanism of plasma membrane-actin cytoskeleton coupling mediated by cooperative action of epsin Ent1 and the HIP1R homolog Sla2 in yeast… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 1 time over the past 90 days. VIEW TWEETS

Citations

Publications citing this paper.
Showing 1-10 of 38 extracted citations

Similar Papers

Loading similar papers…