Molecular-assisted refolding: study of two different ionic forms of recombinant human fibroblast growth factors.

Abstract

Despite several early reports on the refolding-enhancement effect of a stimuli-responsive polymer, Eudragit, the exact mechanism by which Eudragit interacts with protein molecules to improve refolding remains not well-understood. This study provides clear elucidation of the mode of involvement of Eudragit in facilitating the refolding of two ionic forms of… (More)
DOI: 10.1016/j.jbiotec.2009.04.006

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