Molecular aspects of gene transfer and foreign DNA acquisition in prokaryotes with regard to safety issues

  title={Molecular aspects of gene transfer and foreign DNA acquisition in prokaryotes with regard to safety issues},
  author={Matthias Brigulla and W. Wackernagel},
  journal={Applied Microbiology and Biotechnology},
  • Matthias Brigulla, W. Wackernagel
  • Published 2010
  • Medicine, Biology
  • Applied Microbiology and Biotechnology
  • Horizontal gene transfer (HGT) is part of prokaryotic life style and a major factor in evolution. In principle, any combinations of genetic information can be explored via HGT for effects on prokaryotic fitness. HGT mechanisms including transformation, conjugation, transduction, and variations of these plus the role of mobile genetic elements are summarized with emphasis on their potential to translocate foreign DNA. Complementarily, we discuss how foreign DNA can be integrated in recipient… CONTINUE READING
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