Molecular architecture of the neuromuscular junction

  title={Molecular architecture of the neuromuscular junction},
  author={Benjamin W Hughes and L. Kusner and H. Kaminski},
  journal={Muscle & Nerve},
  • Benjamin W Hughes, L. Kusner, H. Kaminski
  • Published 2006
  • Biology, Medicine
  • Muscle & Nerve
  • The neuromuscular junction (NMJ) is a complex structure that serves to efficiently communicate the electrical impulse from the motor neuron to the skeletal muscle to signal contraction. Over the last 200 years, technological advances in microscopy allowed visualization of the existence of a gap between the motor neuron and skeletal muscle that necessitated the existence of a messenger, which proved to be acetylcholine. Ultrastructural analysis identified vesicles in the presynaptic nerve… CONTINUE READING
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