Molecular architecture of a eukaryotic DNA transposase

@article{Hickman2005MolecularAO,
  title={Molecular architecture of a eukaryotic DNA transposase},
  author={Alison Burgess Hickman and Zhanita N Perez and Liqin Zhou and Primrose Musingarimi and Rodolfo Ghirlando and Jenny E. Hinshaw and Nancy L. Craig and Fred Dyda},
  journal={Nature Structural &Molecular Biology},
  year={2005},
  volume={12},
  pages={715-721}
}
Mobile elements and their inactive remnants account for large proportions of most eukaryotic genomes, where they have had central roles in genome evolution. Over 50 years ago, McClintock reported a form of stress-induced genome instability in maize in which discrete DNA segments move between chromosomal locations. Our current mechanistic understanding of… CONTINUE READING