Molecular architecture and assembly principles of Vibrio cholerae biofilms.

  title={Molecular architecture and assembly principles of Vibrio cholerae biofilms.},
  author={Veysel Berk and Jiunn Cn Fong and Graham T. Dempsey and Omer Necati Develioglu and Xiaowei Zhuang and Jan Liphardt and Fitnat H. Yildiz and Steven Chu},
  volume={337 6091},
In their natural environment, microbes organize into communities held together by an extracellular matrix composed of polysaccharides and proteins. We developed an in vivo labeling strategy to allow the extracellular matrix of developing biofilms to be visualized with conventional and superresolution light microscopy. Vibrio cholerae biofilms displayed three distinct levels of spatial organization: cells, clusters of cells, and collections of clusters. Multiresolution imaging of living V… CONTINUE READING
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