Molecular antifungal defenses in subterranean termites: RNA interference reveals in vivo roles of termicins and GNBPs against a naturally encountered pathogen.

@article{Hamilton2012MolecularAD,
  title={Molecular antifungal defenses in subterranean termites: RNA interference reveals in vivo roles of termicins and GNBPs against a naturally encountered pathogen.},
  author={Casey Hamilton and Mark S. Bulmer},
  journal={Developmental and comparative immunology},
  year={2012},
  volume={36 2},
  pages={372-7}
}
Subterranean termites face strong pathogenic pressures from the ubiquitous soil fungus Metarhizium anisopliae, and rely on innate humoral and cellular, as well as behavioral immune defenses for protection. Reticulitermes termites secrete antifungal enzymes that exhibit strong β-1,3-glucanase activity associated with Gram-negative bacteria binding proteins (GNBPs), which prevent M. anisopliae from invading the hemocoel where it can evade immune responses. Molecular evolutionary studies of… CONTINUE READING

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