Molecular and structural patterns of bone regeneration in surgically created defects containing bone substitutes.

@article{Elgali2014MolecularAS,
  title={Molecular and structural patterns of bone regeneration in surgically created defects containing bone substitutes.},
  author={Ibrahim Elgali and Kazuyo Igawa and Anders Palmquist and Maria E Lenner{\aa}s and Wei Xia and SungJin Choi and Ung-il Chung and Omar Omar and Peter Thomsen},
  journal={Biomaterials},
  year={2014},
  volume={35 10},
  pages={3229-42}
}
Several biomaterials have been introduced for bone augmentation. However, information is lacking about the mechanisms of bone regeneration and/or integration of these materials in the recipient bone. This study aimed to determine the molecular and structural events in bone defects after augmentation with synthetic tetrapod-shaped calcium phosphate (Tetrabone; TetraB) compared with natural deproteinized bovine bone (DBB). Defects were created in the epiphyses of rat femurs and filled with TetraB… CONTINUE READING

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