Molecular and pharmacological characterization of muscarinic receptors in retinal pigment epithelium: role in light-adaptive pigment movements.

@article{Phatarpekar2005MolecularAP,
  title={Molecular and pharmacological characterization of muscarinic receptors in retinal pigment epithelium: role in light-adaptive pigment movements.},
  author={Prasad V. Phatarpekar and Simon F. Durdan and Chad M Copeland and Elizabeth Lyla Crittenden and James D. Neece and Dana M. Garc{\'i}a},
  journal={Journal of neurochemistry},
  year={2005},
  volume={95 5},
  pages={
          1504-20
        }
}
Muscarinic receptors are the predominant cholinergic receptors in the central and peripheral nervous systems. Recently, activation of muscarinic receptors was found to elicit pigment granule dispersion in retinal pigment epithelium isolated from bluegill fish. Pigment granule movement in retinal pigment epithelium is a light-adaptive mechanism in fish. In the present study, we used pharmacological and molecular approaches to identify the muscarinic receptor subtype and the intracellular… CONTINUE READING

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