Molecular and immunohistochemical investigation of protein kinase a regulatory subunit type 1A (PRKAR1A) in odontogenic myxomas.

@article{Perdigo2005MolecularAI,
  title={Molecular and immunohistochemical investigation of protein kinase a regulatory subunit type 1A (PRKAR1A) in odontogenic myxomas.},
  author={Paola F Perdig{\~a}o and Sotirios G. Stergiopoulos and Luiz De Marco and Ludmila Matyakhina and Sosipatros A. Boikos and Ricardo Santiago Gomez and Fl{\'a}vio Juliano Garcia Santos Pimenta and Constantine A. Stratakis},
  journal={Genes, chromosomes & cancer},
  year={2005},
  volume={44 2},
  pages={204-11}
}
Odontogenic myxomas are rare benign neoplasms affecting the jaw. Myxomas of bones and other sites occur as part of Carney complex (CNC), a multiple neoplasia syndrome caused by mutations in the PRKAR1A gene, which codes for the regulatory subunit of protein kinase A (PKA). In the present study, 17 odontogenic myxomas from patients without CNC were screened… CONTINUE READING