Molecular and immunochemical characterization of the ionotropic glutamate receptors in the rat heart

@article{Gill1998MolecularAI,
  title={Molecular and immunochemical characterization of the ionotropic glutamate receptors in the rat heart},
  author={Santokh Gill and Olga Pulido and Reudi W. Mueller and P Mcguire},
  journal={Brain Research Bulletin},
  year={1998},
  volume={46},
  pages={429-434}
}
Human Heart Glutamate Receptors—Implications for Toxicology, Food Safety, and Drug Discovery
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N-Methyl-d-aspartate receptor (NMDAR) is a glutamate-gated ionotropic receptor that intervenes in most of the excitatory synaptic transmission within the central nervous system (CNS). Aside from
GLUTAMATE RECEPTORS; FROM BASIC PHARMACOLOGY TO CLINICAL APPLICATIONS
TLDR
The basic biology of glutamate receptors will be explored and a review of the literature for the role of glutamate agonists and antagonists in neurological disease is presented.
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TLDR
Emerging evidence suggests that Glu could play a dual role in mechanisms underlying the maintenance of cellular homeostasis - as an excitatory neurotransmitter in the central neurocrine system and an extracellular signal mediator in peripheral autocrine and/or paracrine tissues.
Review Article: Glutamate Receptors in Peripheral Tissues: Current Knowledge, Future Research, and Implications for Toxicology
TLDR
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Pharmacology of AMPA/Kainate Receptor Ligands and Their Therapeutic Potential in Neurological and Psychiatric Disorders
TLDR
Evidence for advantages of AMPA receptor antagonists over N-methyl-D-aspartate (NMDA) receptor antagonists for symptomatic treatment of neurological and psychiatric conditions, and for minimising neuronal loss occurring after acute neurological diseases, are shown in animal models.
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