Molecular and immunochemical characterization of the ionotropic glutamate receptors in the rat heart
@article{Gill1998MolecularAI, title={Molecular and immunochemical characterization of the ionotropic glutamate receptors in the rat heart}, author={Santokh Gill and Olga Pulido and Reudi W. Mueller and P Mcguire}, journal={Brain Research Bulletin}, year={1998}, volume={46}, pages={429-434} }
99 Citations
Human Heart Glutamate Receptors—Implications for Toxicology, Food Safety, and Drug Discovery
- BiologyToxicologic pathology
- 2007
The GluRs in the heart could be targets for the effects of excitatory compounds and is therefore an important consideration for the safety evaluation of foods and therapeutic products.
Immunochemical localization of the metabotropic glutamate receptors in the rat heart
- BiologyBrain Research Bulletin
- 1999
A Review of Glutamate Receptors II: Pathophysiology and Pathology
- Biology
- 2008
The diseases in which the pathophysiology and pathology are associated, in part, with the glutamate system are explored, including epilepsy, amnesia, anxiety, hyperalgesia and psychosis.
Metabotropic glutamate receptor/phospholipase C system in female rat heart
- BiologyBrain Research
- 2007
Potential Target Sites in Peripheral Tissues for Excitatory Neurotransmission and Excitotoxicity
- BiologyToxicologic pathology
- 2000
Food safety assessment and neurobiotechnology focusing on drugs designed to interact with GluRs should consider these tissues as potential target/effector sites because of their importance in the toxicity of excitatory compounds.
Glutamate-Gated NMDA Receptors: Insights into the Function and Signaling in the Kidney
- BiologyBiomolecules
- 2020
N-Methyl-d-aspartate receptor (NMDAR) is a glutamate-gated ionotropic receptor that intervenes in most of the excitatory synaptic transmission within the central nervous system (CNS). Aside from…
GLUTAMATE RECEPTORS; FROM BASIC PHARMACOLOGY TO CLINICAL APPLICATIONS
- Biology
- 2012
The basic biology of glutamate receptors will be explored and a review of the literature for the role of glutamate agonists and antagonists in neurological disease is presented.
Glutamate signaling in peripheral tissues.
- BiologyEuropean journal of biochemistry
- 2004
Emerging evidence suggests that Glu could play a dual role in mechanisms underlying the maintenance of cellular homeostasis - as an excitatory neurotransmitter in the central neurocrine system and an extracellular signal mediator in peripheral autocrine and/or paracrine tissues.
Review Article: Glutamate Receptors in Peripheral Tissues: Current Knowledge, Future Research, and Implications for Toxicology
- BiologyToxicologic pathology
- 2001
The important tasks for the future will be to clarify the multiple biological roles of the GluRs in neural and non-neural tissues and identify the conditions under in which these are up- or down-regulated, which could provide new therapeutic strategies to target GLURs outside the CNS.
Pharmacology of AMPA/Kainate Receptor Ligands and Their Therapeutic Potential in Neurological and Psychiatric Disorders
- Biology, MedicineDrugs
- 2012
Evidence for advantages of AMPA receptor antagonists over N-methyl-D-aspartate (NMDA) receptor antagonists for symptomatic treatment of neurological and psychiatric conditions, and for minimising neuronal loss occurring after acute neurological diseases, are shown in animal models.
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