Molecular and genetic aspects of the immune responses to hepatitis B viral antigens.

@article{Milich1989MolecularAG,
  title={Molecular and genetic aspects of the immune responses to hepatitis B viral antigens.},
  author={David R. Milich},
  journal={Advances in experimental medicine and biology},
  year={1989},
  volume={257},
  pages={115-33}
}
  • David R. Milich
  • Published 1989 in Advances in experimental medicine and biology
In the absence of an inbred animal model of hepatitis B virus (HBV) infection, several laboratories have chosen to study the murine immune response to HBV-encoded proteins as immunogens as opposed to an infectious agent. This article reviews the immunogenicity, the fine specificity of T and B cell recognition of HBV antigens, and the genetic influences that… CONTINUE READING