Molecular and functional heterogeneity of inward rectifier potassium channels in brain and heart.

Abstract

We have cloned cDNAs encoding three background inward rectifier potassium channels from a mouse brain cDNA library. We designated them mouse brain (MB)- IRK1, MB-IRK2, and MB-IRK3, based on their amino acid sequences and the electrophysiological properties of currents expressed in Xenopus oocytes. Xenopus oocytes injected with cRNAs derived from these… (More)

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