Molecular and functional characterization of ERG, KCNQ, and KCNE subtypes in rat stomach smooth muscle.

@article{Ohya2002MolecularAF,
  title={Molecular and functional characterization of ERG, KCNQ, and KCNE subtypes in rat stomach smooth muscle.},
  author={Susumu Ohya and Keiichi Asakura and Katsuhiko Muraki and Minoru Watanabe and Yuji Imaizumi},
  journal={American journal of physiology. Gastrointestinal and liver physiology},
  year={2002},
  volume={282 2},
  pages={G277-87}
}
Contribution of K(+) channels derived from the expression of ERG, KCNQ, and KCNE subtypes, which are responsible for rapidly and slowly activating delayed rectifier K(+) currents (I(Kr) and I(Ks), respectively) in cardiac myocytes, to membrane currents was examined in stomach circular smooth muscle cells (SMCs). The region-qualified multicell RT-PCR showed that ERG1/KCNE2 transcripts were expressed in rat stomach fundus and antrum SMCs and that KCNQ1/KCNE1 transcripts were expressed in antrum… CONTINUE READING

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