Molecular and functional aspects of PECAM-1/CD31.

  title={Molecular and functional aspects of PECAM-1/CD31.},
  author={Horace M. Delisser and Peter J. Newman and Steven M. Albelda},
  journal={Immunology today},
  volume={15 10},
Among vascular cell adhesion molecules, platelet-endothelial cell adhesion molecule (PECAM-1/CD31) has the distinctive feature of being expressed on several of the major cell types associated with the vascular compartment. This makes it uniquely positioned to mediate multiple and important cell-cell interactions involving platelets, leukocytes and endothelial cells. Thus, PECAM-1 may represent a potential target for new therapeutic agents directed at a variety of pathological states. 

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