Molecular and cytogenetic characterization of a Chinese hamster/human hybrid cell line containing a der (21)t(Ypter-->cenY::cen21-->21qter) chromosome.

@article{Patterson1993MolecularAC,
  title={Molecular and cytogenetic characterization of a Chinese hamster/human hybrid cell line containing a der (21)t(Ypter-->cenY::cen21-->21qter) chromosome.},
  author={David Patterson and Iris Hart and L. W. Lai and Christina Brahe and A Moscetti and Flora Tassone and Elena Raimondi and C. Jones},
  journal={Genomics},
  year={1993},
  volume={15 1},
  pages={
          177-9
        }
}
Human/rodent somatic cell hybrids have been exceedingly useful in assigning human genes and DNA sequences to specific human chromosomes. As new technologies for analyzing the human chromosome complement of such human/rodent hybrid cells become available, it is of critical importance that these be applied to enhance characterization of existing hybrids. This is particularly important since human chromosomes in such hybrids have been observed to rearrange with time. We report here the use of… CONTINUE READING