Molecular and cognitive predictors of the continuum of autistic behaviours in fragile X

@article{Loesch2007MolecularAC,
  title={Molecular and cognitive predictors of the continuum of autistic behaviours in fragile X},
  author={Danuta Z Loesch and Quang Minh Bui and Cheryl Dissanayake and Sally M Clifford and Emma Gould and Danuta Bulhak-Paterson and Flora Tassone and Annette Kimball Taylor and David Hessl and Randi J. Hagerman and Richard M. Huggins},
  journal={Neuroscience & Biobehavioral Reviews},
  year={2007},
  volume={31},
  pages={315-326}
}
The distributions of scores for autistic behaviours obtained from the Autism Diagnostic Observation Scale-Generic (ADOS-G) were investigated in 147 males and females affected with the full mutation in the fragile X mental retardation 1 (FMR1) gene, in 59 individuals with the premutation, and in 42 non-fragile X relatives, aged 4-70 years. The scores representing communication and social interaction were continuously distributed across the two fragile X groups, and they were significantly… CONTINUE READING
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