Molecular and cellular mechanisms of skeletal muscle atrophy: an update

@inproceedings{Fanzani2012MolecularAC,
  title={Molecular and cellular mechanisms of skeletal muscle atrophy: an update},
  author={Alessandro Fanzani and Viviane Marie Conraads and Fabio Penna and Wim Martinet},
  booktitle={Journal of cachexia, sarcopenia and muscle},
  year={2012}
}
Skeletal muscle atrophy is defined as a decrease in muscle mass and it occurs when protein degradation exceeds protein synthesis. Potential triggers of muscle wasting are long-term immobilization, malnutrition, severe burns, aging as well as various serious and often chronic diseases, such as chronic heart failure, obstructive lung disease, renal failure, AIDS, sepsis, immune disorders, cancer, and dystrophies. Interestingly, a cooperation between several pathophysiological factors, including… CONTINUE READING
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