Molecular and cellular aspects of fibrosis following thermal injury.

  title={Molecular and cellular aspects of fibrosis following thermal injury.},
  author={Paul G. Scott and Aziz Ghahary and Edward E. Tredget},
  journal={Hand clinics},
  volume={16 2},
The pathogenesis of hypertrophic scars following thermal injury remains a complex and incompletely understood process but recent investigations into the composition of the tissue itself, the activities of the scar fibroblasts, and the effects of various cytokines and growth factors, have all contributed to the emergence of an increasingly clear picture. Although it may be considered just one example of a broad range of fibroproliferative disorders that afflict many different organs, often in… CONTINUE READING