Molecular and binding characteristics of IP3 receptors in bovine spermatozoa.

@article{Minelli2000MolecularAB,
  title={Molecular and binding characteristics of IP3 receptors in bovine spermatozoa.},
  author={Alba Minelli and Cinzia Allegrucci and Robert A. Rosati and I. Mezzasoma},
  journal={Molecular reproduction and development},
  year={2000},
  volume={56 4},
  pages={
          527-33
        }
}
We have shown the presence of inositol 1,4,5-triphosphate (IP3) receptors in bovine spermatozoa. These receptors are mainly localized and functionally associated with the acrosome region. Molecular characterization of these bovine IP3 receptors has shown that the functional size of the IP3 binding domain is a protein of 66+/-2 kDa, in agreement with the size of both bovine adrenal cortex and bovine adrenal medullar chromaffin cells IP3 receptors. In contrast, bovine cerebellum IP3 receptor… CONTINUE READING