Molecular and antibiofilm approaches to prosthetic joint infection.

  title={Molecular and antibiofilm approaches to prosthetic joint infection.},
  author={Andrej Trampuz and Douglas R. Osmon and Arlen D. Hanssen and James M. Steckelberg and Robin Patel},
  journal={Clinical orthopaedics and related research},
The majority of patients with prosthetic joint replacement (arthroplasty) experience dramatic relief of pain and restoration of satisfactory joint function. In the United States, more than.5 million people have a primary arthroplasty each year. Less than 10% of prosthesis recipients have complications develop during their lifetime, commonly as a result of aseptic biomechanical failure, followed by prosthetic joint infection. The pathogenesis of prosthetic joint infection is related to bacteria… CONTINUE READING