Molecular and Structural Characterization of Polydisperse Polymers and Copolymers by Combining MALDI-TOF Mass Spectrometry with GPC Fractionation
@article{Montaudo1995MolecularAS, title={Molecular and Structural Characterization of Polydisperse Polymers and Copolymers by Combining MALDI-TOF Mass Spectrometry with GPC Fractionation}, author={Giorgio Montaudo and Domenico Garozzo and Maurizio S. Montaudo and Concetto Puglisi and Filippo Samperi}, journal={Macromolecules}, year={1995}, volume={28}, pages={7983-7989} }
Matrix assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) allows detection of large molecules such as those present in synthetic and natural macromolecules. Until recently, it was reported that MALDI-TOF measurements can provide correct molecular weight (MW) averages only for samples with a narrow MW distribution (M w /M n ≤ 1.20). We have now developed a methodology for polydisperse samples. We recorded the GPC trace of two polydisperse polymeric samples…
134 Citations
Molecular Weight Determination and Structural Analysis in Polydisperse Polymers by Hyphenated Gel Permeation Chromatography/Matrix-Assisted Laser Desorption Ionization—Time of Flight Mass Spectrometry
- Materials Science, Chemistry
- 1997
Abstract A method for the determination of molecular weight distribution data for polydisperse polymer samples by MALDI-TOF is reported that involves the fractionation of polydisperse samples through…
Structural Characterization of Aromatic Polyester Resins by Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry
- Chemistry
- 2001
Matrix-assisted laser desorption/ionization (MALDI) mass spectrometry was used to characterize average molecular weights and end-groups of synthetic aromatic polyesters and the same characteristics…
Molecular weight analysis of water-soluble poly(phenylene ethynylene)s using MALDI-TOF MS
- Materials Science, Chemistry
- 2017
Molecular weights of seven poly(phenylene ethynylene)-based water-soluble conjugated polyelectrolytes (CPEs) obtained through Sonogashira coupling are determined by matrix-assisted laser…
Analysis of poly(bisphenol A carbonate) by size exclusion chromatography/matrix-assisted laser desorption/ionization. 1. End group and molar mass determination
- ChemistryRapid communications in mass spectrometry : RCM
- 1999
The results show that the MALDI spectra of the SEC fractions allow not only the detection of linear and cyclic oligomers contained in these samples, but also the simultaneous determination of their average molar masses.
Instrumental effects in the analysis of polymers of wide polydispersity by MALDI mass spectrometry
- Materials Science
- 1997
MS-based analytical strategy for comprehensive molecular characterization of biodegradable poly(lactic-co-glycolic) acid copolymers.
- ChemistryJournal of the American Society for Mass Spectrometry
- 2020
An analytical methodology with mass spectrometry as the core technique was developed for precise characterization of end-groups, size and co-monomeric composition of poly(lactic-co-glycolic) acid…
The influence of matrix and laser energy on the molecular mass distribution of synthetic polymers obtained by MALDI-TOF-MS
- Materials Science
- 2004
Oligomeric cationic polymethacrylates: a comparison of methods for determining molecular weight.
- Biology, Materials ScienceAnalytical chemistry
- 2014
H NMR end-group analysis is therefore an inexpensive and facile, primary quantitative method to estimate the molecular weight of oliogomeric cationic polymethacrylates if suitably distinct end-groups signals are present in the spectrum.
New results on matrix‐assisted laser desorption/ionization mass spectrometry of widely polydisperse hydrosoluble polymers
- Chemistry
- 2002
Polyvinylpyrrolidone (PVP) of molecular weight (Mw) 40 000 and 160 000 and polydispersity of 1.8–2.2 was shown to yield matrix-assisted laser desorption/ionization (MALDI) mass spectra with the…