Molecular and Cellular Pathobiology Extracellular DNA in Pancreatic Cancer Promotes Cell Invasion and Metastasis

@inproceedings{Wen2013MolecularAC,
  title={Molecular and Cellular Pathobiology Extracellular DNA in Pancreatic Cancer Promotes Cell Invasion and Metastasis},
  author={Fushi Wen and Alex Yi-Hao Shen and Andrew Choi and Eugene W. Gerner and Jiaqi Shi},
  year={2013}
}
Aggressive metastasis is the chief cause of the highmorbidity andmortality associated with pancreatic cancer, yet the basis for its aggressive behavior remains elusive. Extracellular DNA (exDNA) is a recently discovered component of inflammatory tissue states. Here, we report that exDNA is present on the surface of pancreatic cancer cells where it is… CONTINUE READING