Molecular and Cellular Pathobiology CD24 Offers a Therapeutic Target for Control of Bladder Cancer Metastasis Based on a Requirement for Lung Colonization

Abstract

Metastasis is lethal inmost bladder cancer patients. Expression of CD24, a glycosyl phosphatidylinositol (GPI)linked sialoglycoprotein and cancer stem cell marker, is associated with metastatic progression in multiple cancer types, yet the role of CD24 in this process remains unclear. While developing a murine model of human metastatic bladder cancer, we… (More)

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@inproceedings{Overdevest2011MolecularAC, title={Molecular and Cellular Pathobiology CD24 Offers a Therapeutic Target for Control of Bladder Cancer Metastasis Based on a Requirement for Lung Colonization}, author={Jonathan B Overdevest and Shibu P Thomas and Glen Kristiansen and Donna E Hansel and S. Rosenbaum Smith and Dan Theodorescu}, year={2011} }