Molecular and Cellular Mechanisms of Action of Tumour Suppressor GAS5 LncRNA

@inproceedings{Pickard2015MolecularAC,
  title={Molecular and Cellular Mechanisms of Action of Tumour Suppressor GAS5 LncRNA},
  author={Mark R. Pickard and Gwyn T. Williams and Bernhard G Herrmann},
  booktitle={Genes},
  year={2015}
}
It is increasingly recognised that lncRNAs play essential regulatory roles in fundamental biological processes and, consequently, that their dysregulation may contribute to major human diseases, including cancer. Better understanding of lncRNA biology may therefore offer new insights into pathogenetic mechanisms and thereby offer novel opportunities for diagnosis and therapy. Of particular interest in this regard is GAS5 lncRNA, which is down-regulated in multiple cancers, with expression… CONTINUE READING
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