Molecular and Applied Aspects of Oxidative Drug Metabolizing Enzymes

Abstract

3 Mitochondrial P450 type enzymes are generally involved in the metabolism of cholesterol derived steroidal compounds. The reactions catalyzed by these enzymes include cholesterol conversion to pregnenolone, II-beta and 18 hydroxylation reactions in adrenal steroid biosynthesis, C-27 hydroxylation of cholic acid in bile acid metabolism, and lalpha and 24… (More)
DOI: 10.1007/978-1-4615-4855-3

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