Molecular analysis of the PHO81 gene of Saccharomyces cerevisiae.

  title={Molecular analysis of the PHO81 gene of Saccharomyces cerevisiae.},
  author={Caretha L Creasy and Stephen L Madden and Lawrence W. Bergman},
  journal={Nucleic acids research},
  volume={21 8},
The PHO81 gene product is a positive regulatory factor required for the synthesis of the phosphate repressible acid phosphatase (encoded by the PHO5 gene) in Saccharomyces cerevisiae. Genetic analysis has suggested that PHO81 may be the signal acceptor molecule; however, the biochemical function of the PHO81 gene product is not known. We have cloned the PHO81 gene and sequenced the promoter. A PHO81-LacZ fusion was shown to be a valid reporter since its expression is regulated by the level of… CONTINUE READING

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