Molecular analysis of the Escherichia coli ruvC gene, which encodes a Holliday junction-specific endonuclease.

@article{Takahagi1991MolecularAO,
  title={Molecular analysis of the Escherichia coli ruvC gene, which encodes a Holliday junction-specific endonuclease.},
  author={Masahiko Takahagi and Hiroshi Iwasaki and Atsuo Nakata and Hideo Shinagawa},
  journal={Journal of bacteriology},
  year={1991},
  volume={173 18},
  pages={5747-53}
}
The Escherichia coli ruvC gene is involved in DNA repair and recombination and encodes an endonuclease that resolves Holliday structure in vitro. The 2.8-kb chromosomal DNA fragment that encompasses the ruvC gene and its flanking regions was cloned and sequenced. Four open reading frames were identified in the order orf17-orf26-ruvC-orf23 immediately upstream of the ruvAB operon, and their orientations are the same as the ruvAB operon, except for orf23. Proteins encoded by orf17, orf26, and… CONTINUE READING
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