Molecular analysis of rubella virus epidemiology across three continents, North America, Europe, and Asia, 1961-1997.

@article{Frey1998MolecularAO,
  title={Molecular analysis of rubella virus epidemiology across three continents, North America, Europe, and Asia, 1961-1997.},
  author={Teryl K. Frey and Emily S. Abernathy and Theresa Bosma and William G. Starkey and Kristin Corbett and Jennifer M Birkenhauer Best and Shigetaka Katow and Scott C. Weaver},
  journal={The Journal of infectious diseases},
  year={1998},
  volume={178 3},
  pages={642-50}
}
E1 gene nucleotide sequences of 63 rubella virus isolates from North America, Europe, and Asia isolated between 1961 and 1997 were compared phylogenetically. Two genotypes were evident: Genotype I contained 60 viruses from North America, Europe, and Japan, and genotype II contained 3 viruses from China and India. The genotype I isolates prior to 1970 grouped into a single diffuse clade, indicating intercontinental circulation, while most post-1975 viruses segregated into geographic clades from… CONTINUE READING