Molecular analysis of parturition via oxytocin receptor expression.

  title={Molecular analysis of parturition via oxytocin receptor expression.},
  author={Tadashi Kimura and Kazuhide Ogita and Kei-Ichi Kumasawa and Takuji Tomimatsu and Tateki Tsutsui},
  journal={Taiwanese journal of obstetrics & gynecology},
  volume={52 2},
In daily obstetric practice, oxytocin is one of the most frequently used drugs to stimulate uterine contraction. However, uterine sensitivity to oxytocin is profoundly different among pregnant women, which may reflect oxytocin receptor (OTR) expression in the uterus. We review here the literature focusing on OTR regulation in the human uterus. Recent progress in molecular biology has augmented our knowledge about OTR regulation in the uterus at the transcription level, although the totality of… CONTINUE READING