Molecular analysis of endometrial hyperplasia in HNPCC-suspicious patients may predict progression to endometrial carcinoma.

@article{Sutter2004MolecularAO,
  title={Molecular analysis of endometrial hyperplasia in HNPCC-suspicious patients may predict progression to endometrial carcinoma.},
  author={Christian Boiero Sutter and Gisela Dallenbach-Hellweg and Dietmar Dipl Ing Schmidt and Joachim M. Baehring and Simone Bielau and Magnus von Knebel Doeberitz and Johannes Gebert},
  journal={International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists},
  year={2004},
  volume={23 1},
  pages={
          18-25
        }
}
Women predisposed to hereditary nonpolyposis colorectal cancer are at high risk of developing endometrial carcinoma at a young age. Hereditary nonpolyposis colorectal cancer-associated endometrial carcinomas are of the endometrioid type, usually arise from complex atypical hyperplasia, and often show microsatellite instability. To identify occult hereditary nonpolyposis colorectal cancer individuals among endometrial carcinoma patients, we examined complex atypical hyperplasias and endometrial… CONTINUE READING
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