Molecular analysis of chromosome 16q regions in dermal analogue tumors of salivary glands: a genetic link to dermal cylindroma?

@article{Choi2002MolecularAO,
  title={Molecular analysis of chromosome 16q regions in dermal analogue tumors of salivary glands: a genetic link to dermal cylindroma?},
  author={Hong Ran Choi and John G. Batsakis and David L Callender and Victor G Prieto and M. A. Luna and A El-naggar},
  journal={The American journal of surgical pathology},
  year={2002},
  volume={26 6},
  pages={778-83}
}
Dermal analogue tumor, an uncommon subtype of basal cell monomorphic adenoma of the parotid gland, has a remarkable clinical and histologic resemblance to dermal cylindroma. Molecular studies of familial and sporadic cylindromas have shown frequent alterations at chromosome 16q12-13 that have recently been found to house the cylindromatosis gene (CYLD). To determine the involvement of the chromosome 16q12-13 region in dermal analogue tumors, we performed loss of heterozygosity analysis using… CONTINUE READING
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