Molecular analysis of a Streptococcus mutans strain exhibiting polymorphism in the tandem gtfB and gtfC genes.


Streptococcus mutans UA101, which was previously demonstrated to be highly cariogenic in gnotobiotic rats, exhibited much lower water-insoluble glucan (IG) synthetic activity compared with that of S. mutans GS5 and was unable to express sucrose-dependent colonization of smooth surfaces in vitro. On the basis of Southern and Western blot (immunoblot… (More)


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