Molecular analysis of a Streptococcus mutans strain exhibiting polymorphism in the tandem gtfB and gtfC genes.

Abstract

Streptococcus mutans UA101, which was previously demonstrated to be highly cariogenic in gnotobiotic rats, exhibited much lower water-insoluble glucan (IG) synthetic activity compared with that of S. mutans GS5 and was unable to express sucrose-dependent colonization of smooth surfaces in vitro. On the basis of Southern and Western blot (immunoblot… (More)

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