Molecular analysis of HLA allelic frequencies and haplotypes in Jordanians and comparison with other related populations.

@article{SnchezVelasco2001MolecularAO,
  title={Molecular analysis of HLA allelic frequencies and haplotypes in Jordanians and comparison with other related populations.},
  author={Pablo S{\'a}nchez-Velasco and Naif S Karadsheh and Alfredo Garc{\'i}a-Mart{\'i}n and Carlos Ru{\'i}z de Alegr{\'i}a and Francisco Leyva-Cob{\'i}an},
  journal={Human immunology},
  year={2001},
  volume={62 9},
  pages={901-9}
}
Twenty alleles for the locus human leukocyte antigen (HLA-A) and 46 for the HLA-B locus were detected in Jordanians. This indicates the existence of high polymorphism in this area. The most frequent HLA class I alleles found were A*0201 (0.1344), B*0713 (0.1724), and C*0502 (0.1793). Twenty-six different alleles in the Jordanian population were identified for the DRB1 locus being the DRB1*0704 (0.2552), DRB1*0401 (0.1965), and DRB1*1501 (0.0896) the most frequent. Common DQA1 alleles were DQA1… CONTINUE READING