Molecular alterations in the respiratory chain of rat liver after chronic ethanol consumption.

@article{Thayer1981MolecularAI,
  title={Molecular alterations in the respiratory chain of rat liver after chronic ethanol consumption.},
  author={William Sydney Thayer and Emanuel Rubin},
  journal={The Journal of biological chemistry},
  year={1981},
  volume={256 12},
  pages={6090-7}
}
Mitochondria, submitochondrial particles, and hepatocytes prepared from the livers of rats treated chronically with ethanol (36% calories, 40 days) exhibited significant alterations in the content of specific respiratory chain components. As measured by heme absorbance, the amounts of substrate-reducible cytochromes aa3 and b were each decreased about 50%, while the amount of cytochromes c plus c1 was unchanged after chronic ethanol treatment. The amounts of extractable flavin and ubiquinone… CONTINUE READING

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