Molecular alterations in metaplastic breast carcinoma.

  title={Molecular alterations in metaplastic breast carcinoma.},
  author={Caroline Louise Cooper and Rooshdiya Z. Karim and Christina I. Selinger and Hugh Carmalt and Cheok Soon Lee and Sandra A. O'Toole},
  journal={Journal of clinical pathology},
  volume={66 6},
Metaplastic carcinoma of the breast is a rare and heterogeneous subtype of breast carcinoma with a generally poor outcome, and few therapeutic options once disease recurs or progresses. Metaplastic carcinomas of the breast are usually of a larger size at diagnosis, with less frequent nodal metastasis compared with invasive ductal carcinoma no special type, and lack hormone and HER2 receptor expression. Recent research has revealed some potentially actionable genetic changes in a subset of these… CONTINUE READING
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