Molecular alterations in endometrial and ovarian clear cell carcinomas: clinical impacts of telomerase reverse transcriptase promoter mutation

@article{Huang2015MolecularAI,
  title={Molecular alterations in endometrial and ovarian clear cell carcinomas: clinical impacts of telomerase reverse transcriptase promoter mutation},
  author={Hsien-Neng Huang and Y C Chiang and Wen Fang Cheng and Chi An Chen and M J Lin and Kuan-Ting Kuo},
  journal={Modern Pathology},
  year={2015},
  volume={28},
  pages={303-311}
}
Recently, mutations of telomerase reverse transcriptase (TERT) promoter were found in several types of cancer. A few reports demonstrate TERT promoter mutations in ovarian clear cell carcinomas but endometrial clear cell carcinoma has not been studied. The aims of this study were to compare differences of molecular alterations and clinical factors, and identify their prognostic impact in endometrial and ovarian clear cell carcinomas. We evaluated mutations of the TERT promoter and PIK3CA… CONTINUE READING

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