• Corpus ID: 40496720

Molecular adsorbent recirculating system ( MARS ) dialysis for fulminant hepatic failure due to paracetamol overdose in children

  title={Molecular adsorbent recirculating system ( MARS ) dialysis for fulminant hepatic failure due to paracetamol overdose in children},
  author={Adrian COVICa and Paul GUSBETH-TATOMIRa and Carmen VOLOVATa and David J. A. GOLDSMITHc},
Paracetamol is a widely used drug, accidental overdosing being particularly encountered in children. The resulting acute liver failure is a therapeutic challenge. There is little agreement on the optimal therapy in paracetamol overdose. Gastric lavage, activated charcoal ingestion and N-acetylcysteine administration are usually effective just shortly after the poisoning, whereas the usefulness of high-flux haemodialysis and haemoperfusion is controversial. Recently, use of “liver dialysis” (or… 
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