Molecular aberrations, targeted therapy, and renal cell carcinoma: current state-of-the-art

Abstract

Renal cell carcinoma (RCC) is among the most prevalent malignancies in the USA. Most RCCs are sporadic, but hereditary syndromes associated with RCC account for 2–3 % of cases and include von Hippel-Lindau, hereditary leiomyomatosis, Birt-Hogg-Dube, tuberous sclerosis, hereditary papillary RCC, and familial renal carcinoma. In the past decade, our… (More)
DOI: 10.1007/s10555-014-9533-1

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