Molecular Therapeutic Approaches for Pediatric Acute Myeloid Leukemia


Approximately two-thirds of children with acute myeloid leukemia (AML) are cured with intensive multi-agent chemotherapy. However, refractory and relapsed AML remains a significant source of childhood cancer mortality, highlighting the need for new therapies. Further therapy intensification with traditional cytotoxic chemotherapy in pediatric AML is not… (More)
DOI: 10.3389/fonc.2014.00055


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