Molecular Studies of T Cell Recognition and Cross-Reactivity: A Dissertation

@inproceedings{Shen2012MolecularSO,
  title={Molecular Studies of T Cell Recognition and Cross-Reactivity: A Dissertation},
  author={Zu Ting Shen},
  year={2012}
}
Intracellular pathogens are recognized by a specialized subset of lymphocytes known as CD8+ T cells. Pathogen recognition by CD8+ T cells occurs through binding of T cell receptors (TCR) to processed antigens in complex with major histocompatibility complex (MHC) class I proteins. TCR engagement of antigens in complex with MHC class I typically lead to cytotoxic CD8+ T cell responses, which result in pathogen clearance. Due to the large number of foreign antigens that might be encountered by… CONTINUE READING

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