Molecular Regulation of Toll-like Receptors in Asthma and COPD

  title={Molecular Regulation of Toll-like Receptors in Asthma and COPD},
  author={Li Zuo and Kurt Lucas and Christopher A. Fortuna and Chia-Chen Chuang and Thomas M. Best},
  booktitle={Front. Physiol.},
Asthma and chronic obstructive pulmonary disease (COPD) have both been historically associated with significant morbidity and financial burden. These diseases can be induced by several exogenous factors, such as pathogen-associated molecular patterns (PAMPs) (e.g., allergens and microbes). Endogenous factors, including reactive oxygen species, and damage-associated molecular patterns (DAMPs) recognized by toll-like receptors (TLRs), can also result in airway inflammation. Asthma is… CONTINUE READING
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