Molecular Regulation of Alternative Polyadenylation (APA) within the Drosophila Nervous System

Abstract

Alternative polyadenylation (APA) is a widespread gene regulatory mechanism that generates mRNAs with different 3'-ends, allowing them to interact with different sets of RNA regulators such as microRNAs and RNA-binding proteins. Recent studies have shown that during development, neural tissues produce mRNAs with particularly long 3'UTRs, suggesting that… (More)
DOI: 10.1016/j.jmb.2017.03.028

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